In vitro vasoactive effects of dexmedetomidine on isolated human umbilical arteries

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effects of vasoactive agents on isolated human umbilical arteries and veins.

ALTURA, BURTON M., D. MALAVIYA, CHARLES F. REICH, AND LOUIS R. ORKIN. Effects of vasoactive agents on isolated human umbilical arteries and veins. Am. J. Physiol. 222(Z): 345-355. 1972.In vitro experiments, using both helically and longitudinally cut human umbilical arteries and veins (HUAV), were designed to determine: I) whether any of the known circulating vasoactive substances can induce co...

متن کامل

Bidirectional effects of dexmedetomidine on human platelet functions in vitro.

Platelets express the imidazoline (I)-receptor, I1 and I2, as well as the α2-adrenoceptor. Although dexmedetomidine, a selective α2-adrenoceptor agonist with some affinity for the I-receptor is expected to affect platelet function, the effects of dexmedetomidine on platelet functions remain unclear. In the present study, we investigated the effects of dexmedetomidine on human platelet functions...

متن کامل

Constriction of Human Umbilical Arteries

Experiments on perfused segments or isolated rings of human umbilical artery showed that the magnitude of their contraction in response to bradykinin, epinephrine, or serotonin depended on the P02 of the perfusing or bathing solution. Constriction to bradykinin varied directly with the O2 tension and was greatest when the Po2 was approximately that of umbilical arterial blood during the transit...

متن کامل

Differential vasoactive effects of sildenafil and tadalafil on cerebral arteries.

Phosphodiesterase 5 (PDE5) is associated with migraine pathophysiology, stroke recovery and vasospasm treatment. The potential vascular interplay of PDE5 inhibitors sildenafil, tadalafil and UK-114,542 was studied by intra- versus extra-luminal administration in rat middle cerebral arteries in vitro and on middle meningeal arteries in vivo. By Western blot PDE5 was detected in both cerebral and...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Bratislava Medical Journal

سال: 2019

ISSN: 1336-0345

DOI: 10.4149/bll_2019_006